TELOMERE DYSFUNCTION COOPERATES WITH EPIGENETIC ALTERATIONS TO IMPAIR MURINE EMBRYONIC STEM CELL FATE COMMITMENT

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment

The precise relationship between epigenetic alterations and telomere dysfunction is still an extant question.Previously, we showed that eroded telomeres lead to differentiation instability in murine embryonic stem cells (mESCs) via DNA hypomethylation at pluripotency-factor promoters.Here, we uncovered that telomerase reverse transcriptase null (Te

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In Situ Analysis of a Silver Nanoparticle-Precipitating Shewanella Biofilm by Surface Enhanced Confocal Raman Microscopy.

Shewanella oneidensis MR-1 is an electroactive bacterium, capable of reducing extracellular insoluble electron acceptors, making it important for both nutrient cycling in nature and microbial electrochemical technologies, such as microbial fuel cells and microbial electrosynthesis.When allowed to anaerobically colonize an Ag/AgCl solid interface, S

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